Tetrodotoxin: Mechanism of Action
نویسندگان
چکیده
منابع مشابه
Mechanism of cardiovascular action of tetrodotoxin in the cat. Block of conduction in peripheral sympathetic fibers.
Tetrodotoxin given to cats in doses of 1 to 10 fi,g/kg iv caused profound cardiovascular depression characterized by decreases in systolic and diastolic blood pressures, pulse pressure, heart rate, force of myocardial contraction, cardiac output and peripheral resistance. These effects were associated with marked inhibition of the responses to stimulation of nerves to the adrenal medulla and th...
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ژورنال
عنوان ژورنال: Science
سال: 1964
ISSN: 0036-8075,1095-9203
DOI: 10.1126/science.144.3616.319-a